Nicolas Coant Selected Research

2-N-(1'-carboxamidino)sphingosine

1/2017

Novel sphingosine kinase-1 inhibitor, LCL351, reduces immune responses in murine DSS-induced colitis.

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Nicolas Coant Research Topics

Disease

5	Neoplasms (Cancer) 01/2021 - 05/2014
4	Colonic Neoplasms (Colon Cancer) 01/2021 - 05/2014
3	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2018 - 01/2014
3	Fibrosis (Cirrhosis) 01/2017 - 01/2009
2	Inflammation (Inflammations) 01/2022 - 01/2018
2	Carcinogenesis 01/2022 - 01/2017
2	Colorectal Neoplasms (Colorectal Cancer) 11/2018 - 01/2018
2	Obesity 01/2018 - 05/2013
2	Colitis 01/2017 - 01/2014
1	Carcinoma (Carcinomatosis) 01/2021
1	Ulcerative Colitis 01/2018
1	Insulin Resistance 01/2018
1	Cicatrix (Scar) 01/2017
1	Splenomegaly 01/2017
1	Body Weight (Weight, Body) 04/2014
1	Overnutrition 05/2013
1	Type 2 Diabetes Mellitus (MODY) 05/2013
1	Chronic Granulomatous Disease 11/2006
1	Reinfection 11/2006
1	Pathologic Processes 11/2006
1	Inborn Genetic Diseases (Disease, Hereditary) 11/2006

Drug/Important Bio-Agent (IBA)

7	Neutral CeramidaseIBA 01/2022 - 12/2016
6	CeramidesIBA 01/2022 - 04/2014
5	EnzymesIBA 01/2021 - 11/2006
5	SphingolipidsIBA 11/2018 - 05/2014
3	CateninsIBA 01/2018 - 05/2014
3	CytokinesIBA 01/2018 - 01/2009
2	thermozymocidin (myriocin)IBA 01/2018 - 04/2014
2	sphingosine kinaseIBA 01/2017 - 01/2014
2	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 01/2017 - 12/2016
2	LipopolysaccharidesIBA 10/2011 - 01/2009
1	Biological ProductsIBA 01/2022
1	HydrolasesIBA 01/2022
1	CeramidasesIBA 01/2021
1	Acid CeramidaseIBA 01/2018
1	Protein Kinase CIBA 01/2018
1	CarcinogensIBA 01/2018
1	Glucose (Dextrose)FDA LinkGeneric 01/2018
1	PalmitatesIBA 01/2018
1	sodium sulfate (sodium bisulfate)FDA LinkGeneric 01/2017
1	Dextrans (Dextran)FDA Link 01/2017
1	IsoenzymesIBA 01/2017
1	2-N-(1'-carboxamidino)sphingosineIBA 01/2017
1	Extracellular Matrix ProteinsIBA 01/2017
1	SphingosineIBA 12/2016
1	AzoxymethaneIBA 12/2016
1	Dextran SulfateIBA 01/2014
1	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2014
1	LipidsIBA 05/2013
1	Glycogen Synthase Kinase 3IBA 10/2011
1	Interleukin-10 (Interleukin 10)IBA 10/2011
1	Toll-Like Receptor 4IBA 10/2011
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2009
1	HDL LipoproteinsIBA 01/2009
1	Interleukin-6 (Interleukin 6)IBA 01/2009
1	neutrophil cytosol factor 67KIBA 11/2006

Therapy/Procedure

5	Therapeutics 01/2021 - 05/2013
1	Immunotherapy 01/2021
1	Intraventricular Infusions 01/2018